William Alford Research Page

Association for Gastrointestinal Motility Diseases, Inc.

http://human-factors.arc.nasa.gov/ihh/psychophysio/technology/index.html - NASA webpage showcasing the work with private sector to investigate GI motility disease. Pictures show Leah Alford receiving the biofeedback used to train the astronauts to overcome the nausea of space flight at the NASA Ames Research Center in Palo Alto, CA. The results of this one-time collaboration merited further investigation and this research and treatment is now being continued by Dr. Hani Rashed at the UT Bowld Hospital in Memphis, TN.

http://www.haukeland.no/sagim/Scientific%20report-Madison.htm - Human embryonic stem cells can be cultured and neuronal stem cell populations have been successfully transplanted to the mouse gastrointestinal tract where they could survive for several weeks, differentiate into neurons, and express neuronal NOS activity. These findings have significant perspectives for the treatment of motility disturbances, such as hypertrophic pyloric stenosis, Hirschsprung's disease and oesophageal achalasia.

http://www.cnn.com/2004/HEALTH/conditions/07/01/celiac.disease.ap/index.html - Celiac disease isn't nearly as rare as once thought: Roughly 3 million Americans may have the severe digestive disorder, most undiagnosed and thus suffering unnecessarily.

http://www.sciencedaily.com/releases/2004/07/040728084924.htm – the depression of patients with diseases having an inflammatory component may actually originate in the immune system, which can be thought of as a sixth sense. “We can't touch, smell, taste, see or hear a virus,” Kelley said, “but we have an organ that senses and responds to infectious pathogens, and transmit this information to the brain. That organ is our immune system.”

http://www.springerlink.com/app/home/contribution.asp?wasp=34uulb80gg7uwmcd455m&referrer=parent&backto=issue,17,22;journal,20,26;linkingpublicationresults,1:110829,1 – Hyperbaric Oxygen Ameliorates Bacterial Translocation in Rats with Mechanical Intestinal Obstruction. CONCLUSIONS: Intestinal obstruction causes bacterial overgrowth and translocation. Hyperbaric oxygen treatment prevents the bacterial translocation effectively.

http://www.ars.usda.gov/research/publications/publications.htm?SEQ_NO_115=155251 – Taking worm eggs may improve bowel disease. There was a significant improvement in IBD disease index in individuals refractory to other conventional forms of treatment that were fed T. suis eggs compared to placebo controls. This observation supports the hypothesis that immunological dysfunction may result from insufficient exposure to certain infections that stimulate a balanced immune response.

http://www.sciencedaily.com/releases/2004/09/040903093237.htm - The enigmatic-but-common condition known as irritable bowel syndrome, or IBS, is caused by an overgrowth of bacteria in the small intestine, a USC researcher has proposed in the Journal of the American Medical Association.

http://www.sciencedaily.com/releases/2004/09/040922070424.htm – Acupuncture is more effective at reducing nausea and vomiting after major breast surgery than the leading medication.

http://www.sciencedaily.com/releases/2004/12/041220024853.htm – Irritable bowel syndrome was significantly more common in people with sleep disturbances than those without sleep disturbances. It's uncertain whether GI disturbances and sleep disturbances cause one another or they are caused by another underlying problem.

http://www.sciencedaily.com/releases/2004/07/040721091234.htm – By reprogramming cells in the immune system, a team of scientists has found a way to boost production of natural killer T cells, with long-term potential for fighting diseases in which the body attacks its own cells.

http://www.carecredit.com/patients/whatis.htm a credit card for medical bills that can allow payments spread over a year, etc with NO interest if paid off within the time allowed.

http://www.intelihealth.com/IH/ihtIH/EMIHC000/9276/9276.html Onlline Medical Dictionary.

http://www.accessdata.fda.gov/scripts/cder/iig/index.cfm FDA's Inactive Ingredient Database for Approved Drugs

http://www.ndrf.org/physicia.htm a listing of Physicians and Medical Facilities that have notified NDRF of their knowledge and specialty in the diagnosis and medical treatment of Dysautonomia.

http://www.sciencedaily.com/releases/2005/12/051228175511.htm According to a study to be published in the American Journal of Physiology-Heart and Circulation Physiology, a typical course of hyperbaric oxygen treatments increases by eight-fold the number of stem cells circulating in a patient's body.

http://health.groups.yahoo.com/group/MedicalEquipmentExchange/ this listserver is for the exchange of medical supplies or equipment among members. Sometimes free, usually very reasonable. A good resource for those with chronic medical needs and who are financially challenged.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16423887&query_hl=1&itool=pubmed_docsum These results suggest that gastrointestinal Candida colonization promotes sensitization against food antigens at least partly due to mast cell-mediated hyperpermeability in gastrointestinal mucosa of mice.

http://www.sciencedaily.com/releases/2004/08/040830083022.htm enzyme may inhibit IBS inflammation

http://www.sciencedaily.com/releases/1999/08/990816065944.htm discovered that these drugs inhibit the activation of a master regulator of the inflammatory response called NF-kappa B. Their research suggests that these compounds, called thiazolidinediones (TZDs), may be an effective new therapy for treating inflammatory bowel disease (IBD) in humans, a debilitating disorder that afflicts millions worldwide.

http://www.sciencedaily.com/releases/2004/07/040723091648.htm Good Bacteria Trigger Proteins To Protect The Gut

http://www.theglobeandmail.com/servlet/ArticleNews/TPStory/LAC/20040630/HBLOOD30/TPHealth/ as strangely unorthodox as it may seem, the process—called immune modulation therapy—may well be a legitimate and effective means of treating heart failure. While this is targeted to heart failure, it would seem that any illness with inflammatory components would be a viable candidate?

http://news.bbc.co.uk/1/hi/health/3692961.stm Cells 'stop talking' in allergy – Scientists believe communication breakdown between cells plays a major role in food allergy.

http://www.sciencedaily.com/releases/2004/05/040504063845.htm FcRn, whose normal job is to preserve antibodies in the circulation. “While a good thing in normal individuals, FcRn could be working too efficiently in patients with lupus and rheumatoid arthritis,” explains Dr. Roopenian. “The consequence is the maintenance of dangerously high levels of autoantibodies.” To test this idea, Dr. Roopenian used mice that normally develop arthritis caused by autoantibodies. His team shows that the elimination or blocking of FcRn resulted in the reduction of autoantibodies and a corresponding protection from arthritis.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10638599 The striking effect of hyperbaric oxygenation therapy in the management of chronic idiopathic intestinal pseudo-obstruction. Chronic idiopathic intestinal pseudo-obstruction is one of the disorders that is most refractory to medical and surgical procedures. Hyperbaric oxygenation resulted not only in relief of the patient's obstructive symptoms but also in a rapid decrease of abnormally accumulated intestinal gas. At last, he could resume oral intake without any critical adverse effects.

http://www.sciencedaily.com/releases/2004/04/040426055041.htm Mothers' Cells Can Cause Immunity Illness In Children

http://www.sciencedaily.com/releases/2004/04/040421232724.htm Protein May Help Prevent Autoimmune Attacks

http://www.thebostonchannel.com/health/1535790/detail.html Stem Cell Research May Lead To Lupus Cure. Procedure Appears To Create New Immune System.

http://www.sciencedaily.com/releases/2004/02/040226070611.htm - - a new study attempted to determine the areas of the human cerebral cortex involved in voluntary contraction of the EAS and the relationship between cerebral cortical activity and two effort levels of willful contraction of this sphincter.

http://www.wired.com/news/technology/medtech/0,61505-0.html - Promising future detox therapy; nanoparticles are injected into the bloodstream, where they circulate through the body, picking up their target toxins; could help with autoimmune diseases if the nanoparticles' receptors were designed to pinpoint the pathogenic antibodies that cause inflammation.